I was trying out some 255gr swc 45lc over 18.5gr of 2400 out of my Blackhawk and hitting low. My sweetie wanted to try and did this on one shot:
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hmm...so I put in a 200gr rnfp over 6.6gr of 231 and she took a whack at it:
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and said "this is a pretty nice gun I like it!"

Sucks to be outshot with your own gun but at least I know if some neer-do-wells try our house my backup is better than I am!