Optimum pocket pistol caliber: 380? 9mm? 357 Sig? 40? 45?

I get the feeling the OP is referring to a hypothetical balance between stopping power and capacity. Is 5 .45s "more" than 7 9mms, or the opposite, etc.

There are many metrics you could use to do this, total bullet weight in the gun, total kinetic energy of all the rounds combined, total mass*velocity*numberRounds, etc etc. All of them would lead to different, and probably useless, conclusions.

Ultimately this is a caliber question, and they all stop the same above .380. So the answer is 9mm.

If you bring concealment into it, then it becomes a personal question. If you can conceal a CM9, 9mm. If you can't, .380.

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